2-Methylpiperidine → HCID 13336378, compound

Participants

Reaction Steps

The procedure of Example 24 is followed using ethyl 2-phenylquinazoline-4-carboxylate (3 g), 2-methylpiperidine (3 ml), a 1.6M solution of butyllithium in hexane (15 ml) and tetrahydrofuran (20 ml) as the starting materials. After recrystallisation from ethanol, 2-methyl-1-[(2-phenylquinazolin-4yl)-carbonyl]-piperidine (1.7 g), melting at 150° C., is obtained.

Provenance & Evidence