Sodium Methoxide → HCID 178423727, compound

HRID 1788780Notes

Reaction equation

HRID 1788780 reaction equation
[CH3:1][C:2]1[CH:7]=[C:6]([C:8]2[C:16]3[N:15]=[N:14][NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[C:5]([OH:17])=[CH:4][CH:3]=1.[CH3:18][O-:19].[Na+]>C1(C)C(C)=CC=CC=1>[CH2:5]([C:4]1[CH:3]=[C:2]([CH3:1])[CH:7]=[C:6]([C:8]2[C:16]3[N:15]=[N:14][NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[C:18]=1[OH:19])[C:4]1[CH:3]=[C:2]([CH3:1])[CH:7]=[C:6]([C:8]2[C:16]3[N:15]=[N:14][NH:13][C:12]=3[CH:11]=[CH:10][CH:9]=2)[C:5]=1[OH:17]

Participants

4

Reactant 2

HCID 10942334Sodium MethoxideHCID 178426830HCID 178426830, compound2×

Product 1

HCID 178423727HCID 178423727, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 7237O-XyleneSolvent

Procedure

6.2 g of the Mannich base obtained in Example 1 and 4-methyl-6benzotriazolyl-phenol 4.5 g were dissolved in 200 ml of xylene, and sodium methylate (28% methanol solution) 0.2 g was added. The solution was heated with stirring under reflux at 140°-150° C. for 10 hours with a stream of nitrogen. After distilling of the solvent, and recrystallizing the residue from xylene, the desired product 2,2'-methylene-bis-(4methyl-6-benzotriazolyl-phenol) was obtained in 95% yield.

Workup

  1. temperatureThe solution was heated
  2. temperatureunder reflux at 140°-150° C. for 10 hours with a stream of nitrogen
  3. distillationAfter distilling of the solvent
  4. customrecrystallizing the residue from xylene

Sources & evidence

ORD record
ord-14408afd0ea04118a6b2aec746408141
Source dataset
uspto-grants-1987_08
Patent number
US04684679

Reaction notes

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