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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788795Generated: November 1, 2026

Methanol → HCID 66633824, compound

https://huagongshe.com/reaction/1788795

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantHCID 12217806HCID 12217806—
ProductHCID 66633824HCID 66633824—

Reaction Steps

wherein R4 to R7 are as defined above, in methanol in an amount of 1.5 to 10 times by volume of nitrophthalide and a reaction temperature of 50° to 80° C. for a reaction period of 8 to 36 hours to produce a phthalide isoquinoline represented by the general formula (III): ##STR11##

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04684732
Source datasetuspto-grants-1987_08
ORD IDord-39e3a70ecded4f8ea6d40804995deae2
Source noteuspto-grants-1987_08