反应详情

N-Benzyloxycarbonyl 3,4-dihydroxyphenylglycine (0.79 g, 2.5 mmole) in acetic acid (10 ml) was treated with sulphuryl chloride (0.2 ml), stirred at room temperature for two hours then diluted with ethyl acetate (50 ml), washed with water (2×3 ml) and brine (20 ml), dried and evaporated to a gum which was crystallized from chloroform, 0.36 g, 41%, mp 141°-143°.

1. washwashed with water (2×3 ml) and brine (20 ml)
2. customdried
3. customevaporated to a gum which
4. customwas crystallized from chloroform, 0.36 g, 41%, mp 141°-143°