Sodium Bicarbonate → HCID 23683695, compound

HRID 1788835Notes

Reaction equation

HRID 1788835 reaction equation
[O:1]=[C:2]1[N:8]2[CH:4]([S:5][C:6]([O:22][C:23]3[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=3)=[C:7]2[C:9]([O:11]CC2C=CC([N+]([O-])=O)=CC=2)=[O:10])[CH2:3]1.C(=O)(O)[O-].[Na+:34]>O1CCOCC1.[Pd]>[O:1]=[C:2]1[N:8]2[CH:4]([S:5][C:6]([O:22][C:23]3[CH:28]=[CH:27][C:26]([CH3:29])=[CH:25][CH:24]=3)=[C:7]2[C:9]([O-:11])=[O:10])[CH2:3]1.[Na+:34]

Participants

5

Reactant 2

HCID 516892Sodium BicarbonateHCID 13118255HCID 13118255, compound

Product 1

HCID 23683695HCID 23683695, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 312751,4-DioxaneSolvent

Procedure

To a solution of 53 mg of 4-nitrobenzyl 7-oxo-3-(4-tolyloxy)-4-thia-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate in dioxan was added an aqueous solution of 10 mg of sodium bicarbonate, and 50 mg of palladium on charcoal (10%). The mixture was hydrogenated with shaking at 50 p.s.i. for 90 minutes.

Sources & evidence

ORD record
ord-8d0305e3f8b44de28230f95fd82629e7
Source dataset
uspto-grants-1987_08
Patent number
US04684640

Reaction notes

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