Sodium Bicarbonate → HCID 23708854, compound

HRID 1788849Notes

Reaction equation

HRID 1788849 reaction equation
[O:1]=[C:2]1[N:8]2[CH:4]([S:5][C:6]([O:22][C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:32])([F:31])[F:30])[CH:24]=3)=[C:7]2[C:9]([O:11]CC2C=CC([N+]([O-])=O)=CC=2)=[O:10])[CH2:3]1.C(=O)(O)[O-].[Na+:37]>O1CCOCC1.O.[Pd]>[O:1]=[C:2]1[N:8]2[CH:4]([S:5][C:6]([O:22][C:23]3[CH:28]=[CH:27][CH:26]=[C:25]([C:29]([F:31])([F:32])[F:30])[CH:24]=3)=[C:7]2[C:9]([O-:11])=[O:10])[CH2:3]1.[Na+:37]

Participants

6

Reactant 2

HCID 516892Sodium BicarbonateHCID 13578067HCID 13578067, compound

Product 1

HCID 23708854HCID 23708854, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

A mixture of a solution of 602 mg of 4-nitrobenzyl 7-oxo-3-(3-trifluoromethylphenoxy)-4-thia-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate in dioxan and 108 mg sodium bicarbonate in water, and 10% palladium/charcoal was hydrogenated at 50 psi at 25° for 60 minutes.

Sources & evidence

ORD record
ord-a4cfa4d84dac4bab831418d092d51e52
Source dataset
uspto-grants-1987_08
Patent number
US04684640

Reaction notes

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