Sodium Bicarbonate → HCID 23708855, compound

HRID 1788851Notes

Reaction equation

HRID 1788851 reaction equation
[C:1]1([O:11][C:12]2[S:18][CH:17]3[N:14]([C:15](=[O:19])[CH2:16]3)[C:13]=2[C:20]([O:22]CC2C=CC([N+]([O-])=O)=CC=2)=[O:21])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.C(=O)(O)[O-].[Na+:37]>O1CCOCC1.O.[Pd]>[C:1]1([O:11][C:12]2[S:18][CH:17]3[N:14]([C:15](=[O:19])[CH2:16]3)[C:13]=2[C:20]([O-:22])=[O:21])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.[Na+:37]

Participants

6

Reactant 2

HCID 516892Sodium BicarbonateHCID 13578073HCID 13578073, compound

Product 1

HCID 23708855HCID 23708855, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

A mixture of a solution of 800 mg of 4-nitrobenzyl 3-(1-naphthyloxy)-7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate in dioxan and 150 mg of sodium bicarbonate in water, and 10% palladium/charcoal was hydrogenated at 50 psi at 25° for 60 minutes.

Sources & evidence

ORD record
ord-5f54f4ebec484876b29f0018a9c011bd
Source dataset
uspto-grants-1987_08
Patent number
US04684640

Reaction notes

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