Sodium Bicarbonate → HCID 131715229, compound

HRID 1788853Notes

Reaction equation

HRID 1788853 reaction equation
[CH3:1][C:2]1[CH:29]=[CH:28][C:5]([S:6][C:7]2[S:13][CH:12]3[N:9]([C:10](=[O:14])[CH2:11]3)[C:8]=2[C:15]([O:17]CC2C=CC([N+]([O-])=O)=CC=2)=[O:16])=[CH:4][CH:3]=1.C(=O)(O)[O-].[Na+:34]>O1CCOCC1.O.[Pd]>[CH3:1][C:2]1[CH:3]=[CH:4][C:5]([S:6][C:7]2[S:13][CH:12]3[N:9]([C:10](=[O:14])[CH2:11]3)[C:8]=2[C:15]([O-:17])=[O:16])=[CH:28][CH:29]=1.[Na+:34]

Participants

6

Reactant 2

HCID 516892Sodium BicarbonateHCID 131715231HCID 131715231, compound

Product 1

HCID 131715229HCID 131715229, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 962WaterSolventHCID 312751,4-DioxaneSolvent

Procedure

A mixture of a solution of 70 mg of 4-nitrobenzyl 3-(4-methylthiophenoxy)-7-oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene-2-carboxylate in dioxan and 13 mg of sodium bicarbonate in water, and 10% palladium/charcoal was hydrogenated at 50 psi at 35° for 60 minutes.

Sources & evidence

ORD record
ord-708832323170435e8c8a68dfd1f9ceec
Source dataset
uspto-grants-1987_08
Patent number
US04684640

Reaction notes

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