HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acrylate → 4-Ethoxycarbonylethyl-1-formylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acrylate | HCID 8821 | — |
| Reactant | 1-Piperazinecarboxaldehyde | HCID 82191 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-Ethoxycarbonylethyl-1-formylpiperazine | HCID 14399785 | 96.6% |
Reaction Steps
Ethyl acrylate (326 g) and chloroform (2 liters) are added to 1-formylpiperazine (320 g) and the mixture is stirred at room temperature for 3 days. The solvent is evaporated under reduced pressure to yield crude 4-ethoxycarbonylethyl-1-formylpiperazine (580 g) as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04686221 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-01666c198ac543a5af6a980a234f5f81 |
| Source note | uspto-grants-1987_08 |