Triethylamine → N-[2-benzyl-1-(3-bromobenzoyl)piperidin-4-yl]-2,2,2-trifluoro-N-(quinolin-4-ylmethyl)acetamide
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[OH:7])[cH:8][cH:9][cH:10]1.[CH2:15]([c:16]1[cH:17][cH:18][cH:19][cH:20][cH:21]1)[CH:22]1[NH:23][CH2:24][CH2:25][CH:26]([N:28]([C:29]([C:30]([F:31])([F:32])[F:33])=[O:34])[CH2:35][c:36]2[cH:37][cH:38][n:39][c:40]3[cH:41][cH:42][cH:43][cH:44][c:45]23)[CH2:27]1.[CH3:46][CH2:47][N:48]([CH2:49][CH3:50])[CH2:51][CH3:52].[S:11]([Cl:12])([Cl:13])=[O:14]>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:7])[N:23]2[CH:22]([CH2:15][c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)[CH2:27][CH:26]([N:28]([C:29]([C:30]([F:31])([F:32])[F:33])=[O:34])[CH2:35][c:36]3[cH:37][cH:38][n:39][c:40]4[cH:41][cH:42][cH:43][cH:44][c:45]34)[CH2:25][CH2:24]2)[cH:8][cH:9][cH:10]1Participants
5
Sources & evidence
- ORD record
- ord-80f1e4d88ee148d5901fd0e2de198c39
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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