HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dichlorobenzaldehyde → (3-Oxetanyl) 2-(2,3-dichlorophenylmethylene)-3-oxobutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dichlorobenzaldehyde | HCID 35745 | — |
| Reactant | 3-Oxetanyl 3-oxobutanoate | HCID 20189329 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Catalyst | Hexanoic Acid | HCID 8892 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | (3-Oxetanyl) 2-(2,3-dichlorophenylmethylene)-3-oxobutanoate | HCID 57031759 | 121.1% |
Reaction Steps
A solution of 2,3-dichlorobenzaldehyde (1.33 g, 7.6 mmoles), 3-oxetanyl 3-oxobutanoate (1.2 g, 7.6 mmoles), piperidine (6 drops) and hexanoic acid (8 drops) in dry benzene (80 ml) was heated at reflux using a Dean and Stark apparatus. The solution was allowed to cool to room temperature and the solvent removed in vacuo to leave the sub-title compound as an oil 2.9 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04686217 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-237a8a17b95a433a9d6231ded81408ce |
| Source note | uspto-grants-1987_08 |