Ethyl 3-ethoxycarbonyloxy-1,4-dihydro-1,4-dioxo-2-naphthoate → HCID 178470044, compound

HRID 1789082Notes

Reaction equation

HRID 1789082 reaction equation
C(OC([O:6][C:7]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](=[O:18])[C:8]=1[C:19]([O:21][CH2:22][CH3:23])=[O:20])=O)C>O1CCCC1>[OH:6][C:7]1[C:16](=[O:17])[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9](=[O:18])[C:8]=1[C:19]([O:21][CH2:22][CH3:23])=[O:20]

Participants

3

Reactant 1

HCID 13912855Ethyl 3-ethoxycarbonyloxy-1,4-dihydro-1,4-dioxo-2-naphthoate

Product 1

HCID 178470044HCID 178470044, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

To the tetrahydrofuran solution under water cooling was added a solution of ethyl 3-ethoxycarbonyloxy-1,4-dihydro-1,4-dioxo-2-naphthoate, obtained by the procedure of Referential Example 22(1) using 3.41 g of ethyl 3-hydroxy-1,4-dihydro-1,4-dioxo-2-naphthoate, in 10 ml of tetrahydrofuran. The mixture was stirred at room temperature for 2 hours. The reaction solution was poured into 100 ml of ethanol, and the resulting crystals were collected by filtration and recrystallized from chloroform - ethanol to give the title compound, m.p. 224°-227° C., yield of 3.70 g.

Sources & evidence

ORD record
ord-669afe21a6c94457b614431828ff5378
Source dataset
uspto-grants-1987_08
Patent number
US04686292

Reaction notes

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