Sodium Hydroxide → HCID 178434071, compound

HRID 1789239Notes

Reaction equation

HRID 1789239 reaction equation
[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1.[OH-].[Na+].[Cl-].[Ca+2:22].[Cl-]>O>[Ca:22].[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1

Participants

5

Reactant 3

HCID 14798Sodium HydroxideHCID 5284359Calcium ChlorideHCID 178434070HCID 178434070, compound

Product 1

HCID 178434071HCID 178434071, compoundYield 79%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent2×

Procedure

In 50 ml. of water is suspended 2.85 g. of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-hydroxypyrazole and the suspension is dissolved in about 5 ml. of a 2N aqueous solution of sodium hydroxide. A solution of 1.11 g. of calcium chloride in 10 ml. of water is added and the resulting mixture is stirred. The so separated precipitates are recovered by filtration and dried to give 2.4 g. of the desired product as white powder melting at about 260° C. Yield 79.0%.

Workup

  1. customThe so separated
  2. customprecipitates
  3. filtrationare recovered by filtration
  4. customdried
  5. customto give 2.4 g

Sources & evidence

ORD record
ord-b66e7becec724b6491382205cc770ac9
Source dataset
uspto-grants-1987_08
Patent number
US04687858

Reaction notes

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