Hydrochloric Acid → HCID 178434072, compound

HRID 1789241Notes

Reaction equation

HRID 1789241 reaction equation
[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1.Cl>>[ClH:15].[CH3:1][N:2]1[C:6]([OH:7])=[C:5]([C:8](=[O:17])[C:9]2[CH:14]=[CH:13][C:12]([Cl:15])=[CH:11][C:10]=2[Cl:16])[C:4]([CH3:18])=[N:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178434070HCID 178434070, compound

Product 1

HCID 178434072HCID 178434072, compoundYield 57.1%

Procedure

To 0.3 g of 1,3-dimethyl-4-(2,4-dichlorobenzoyl)-5-hydroxypyrazole is added 2 ml. of conc. HCl and the resulting mixture is stirred at room temperature for 6 hours. After completion of the reaction, the reaction mixture is allowed to cool and the so separated desired product is recovered by filtration. The product is washed with a small amount of methanol and then with n-hexane and next dried to give 0.20 g. of the desired product as white powders having a melting point of 115°-125° C. (with decomp.) Yield 57.1%.

Workup

  1. customAfter completion of the reaction
  2. temperatureto cool
  3. customthe so separated desired product
  4. filtrationis recovered by filtration
  5. washThe product is washed with a small amount of methanol
  6. dry with materialwith n-hexane and next dried
  7. customto give 0.20 g

Sources & evidence

ORD record
ord-d4dd3618695e44f1baef211e20a3427b
Source dataset
uspto-grants-1987_08
Patent number
US04687858

Reaction notes

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