Sulfuric Acid → HCID 54146119, compound

HRID 1789391Notes

Reaction equation

HRID 1789391 reaction equation
[CH3:1][C@@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][C@@H:3]1[C:11](Cl)=[O:12].S(=O)(=O)(O)O.[CH3:19]COCC>>[CH3:1][C@@H:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][C@@H:3]1[C:11](=[O:12])[CH3:19]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 3283Diethyl EtherHCID 53651586HCID 53651586, compound

Product 1

HCID 54146119HCID 54146119, compoundYield 92%

Procedure

cis-1-(2,3-Dihydro-1-methyl-1H-inden-2-yl)ethanone is prepared by the treatment of cis-2,3-dihydro-1-methyl-1H-indene-2-carboxylic acid chloride with ethoxymagnesiummalonic acid ethyl ester in dry ether and thereafter by the treatment of sulfuric acid according to the publication (Reynolds G. A. and Hauser, C. B., Org. Synth. 30 (1957) 70). The yield is 92%.

Sources & evidence

ORD record
ord-0c8bd1726a624b558cf9760fcb686e24
Source dataset
uspto-grants-1987_08
Patent number
US04689339

Reaction notes

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