Sulfuric Acid → HCID 13649405, compound

HRID 1789393Notes

Reaction equation

HRID 1789393 reaction equation
[CH3:1][CH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH3:11])[CH:9]=2)[CH:4]=[C:3]1[C:12]([OH:14])=[O:13].C(OC(=O)C(C(=O)C)CC1C=CC(C)=CC=1)C.S(=O)(=O)(O)O>>[CH3:1][C:2]1[C:10]2[C:5](=[CH:6][CH:7]=[C:8]([CH3:11])[CH:9]=2)[CH2:4][C:3]=1[C:12]([OH:14])=[O:13]

Participants

4

Reactant 3

HCID 1118Sulfuric AcidHCID 15338833HCID 15338833, compoundHCID 15588516HCID 15588516, compound

Product 1

HCID 13649405HCID 13649405, compoundYield 59%

Procedure

The 1,6-dimethyl-indene-2-carboxylic acid can be prepared by the treatment of α-acetyl-4-methylbenzenepropanoic acid ethyl ester with sulfuric acid (Shadbolt, R. S., J. Chem. Soc. (C), (1970) 920). Recrystallization from ethanol, m.p. 174°-182° C. Yield 59%.

Workup

  1. customRecrystallization from ethanol, m.p. 174°-182° C

Sources & evidence

ORD record
ord-7ea4f8fc554c4262acbd33d788d8a118
Source dataset
uspto-grants-1987_08
Patent number
US04689339

Reaction notes

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