Thionyl Chloride → HCID 13649411, compound

HRID 1789400Notes

Reaction equation

HRID 1789400 reaction equation
[CH3:1][C:2]1([C:11]([OH:13])=O)[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1.S(Cl)([Cl:16])=O>>[CH3:1][C:2]1([C:11]([Cl:16])=[O:13])[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 153388422-methyl-2,3-dihydro-1H-indene-2-carboxylic acid

Product 1

HCID 13649411HCID 13649411, compound

Procedure

A stirred mixture of 2,3-dihydro-2-methyl-1H-indene-2-carboxylic acid (6.70 g) and thionyl chloride (70 ml) is heated under reflux for 14 hr. The ecess of thionyl chloride is removed and the acid chloride is distilled. Yield 5.35 g, 72%, bp. 93°-98° C./3 mmHg.

Workup

  1. temperatureis heated
  2. temperatureunder reflux for 14 hr
  3. customThe ecess of thionyl chloride is removed
  4. distillationthe acid chloride is distilled

Sources & evidence

ORD record
ord-1b094d5a56494e2da452893b6b974dbc
Source dataset
uspto-grants-1987_08
Patent number
US04689339

Reaction notes

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