Bromine → 2-Bromo-1-(2,3-dihydro-2-methyl-1h-inden-2-yl)ethanone

HRID 1789401Notes

Reaction equation

HRID 1789401 reaction equation
[CH3:1][C:2]1([C:11](=[O:13])[CH3:12])[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1.[Br:14]Br>C(Cl)Cl>[Br:14][CH2:12][C:11]([C:2]1([CH3:1])[CH2:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3]1)=[O:13]

Participants

4

Reactant 2

HCID 24408BromineHCID 15338843HCID 15338843, compound

Product 1

HCID 153388442-Bromo-1-(2,3-dihydro-2-methyl-1h-inden-2-yl)ethanone

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent2×

Procedure

1-(2,3-Dihydro-2-methyl-1H-inden-2-yl)ethanone (3.69 g) in methylene chloride (40 ml) is stirred and cooled at 10° C. during the dropwise addition of bromine (2.82 g)/methylene chloride (10 ml). Work-up of the resultant solution gives 2-bromo-1-(2,3-dihydro-2-methyl-1H-inden-2-yl)ethanone.

Sources & evidence

ORD record
ord-85a2fa7645354306a0bcb4aae40fe67f
Source dataset
uspto-grants-1987_08
Patent number
US04689339

Reaction notes

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