Benzaldehyde → 1-methyl-2-phenyl-1H-imidazo[4,5-c]quinoline

HRID 1789443Notes

Reaction equation

HRID 1789443 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH:12][CH3:13])=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH:14](=O)[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:13][N:12]1[C:11]2[C:10]3[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=3[N:4]=[CH:3][C:2]=2[N:1]=[C:14]1[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 240BenzaldehydeHCID 13958346HCID 13958346, compound

Product 1

HCID 100381871-methyl-2-phenyl-1H-imidazo[4,5-c]quinoline

Procedure

Following the general method of Example 195, Step B, 3-amino-4-(methylamino)quinoline was reacted with benzaldehyde to provide 1-methyl-2-phenyl-1H-imidazo[4,5-c]quinoline, melting point 168-170° C. Analysis: Calculated for C17H13N3 : % C, 78.7; % H, 5.1; % N, 16.2. Found: % C, 78.9; % H, 5.0; % N, 16.1.

Sources & evidence

ORD record
ord-4558a0d0ae84408dbd0ef2b8670238d8
Source dataset
uspto-grants-1987_08
Patent number
US04689338

Reaction notes

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