HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 178480903, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | N-[4-(1-Hydroxy-2-(1H-imidazol-1-yl)ethyl]phenyl]methanesulfonamide | HCID 13763390 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178480903 | HCID 178480903 | — |
Reaction Steps
Heat a solution of 4.0 g (14.2 mmole) of (±)-N-[4-[1-hydroxy-2-(1H-imidazol-1-yl)ethyl]phenyl]methanesulfonamide, 2 ml (32.1 mmole) of iodomethane and 50 ml methanol in a glass pressure tube to 80° C. for 24 hours. Remove the solvent in vacuo. Crystallize the residue from acetone. Recrystallize from acetone to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04689341 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-057cda30ba974403950321e96ed564fa |
| Source note | uspto-grants-1987_08 |