2,3-Dichloroquinoxaline → HCID 22036340, compound

HRID 1789673Notes

Reaction equation

HRID 1789673 reaction equation
[O:1]([CH2:8][CH2:9][OH:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:11][C:12]1[C:21](Cl)=[N:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:13]=1.O(C(C)(C)C)[K]>>[Cl:11][C:12]1[C:21]([O:10][CH2:9][CH2:8][O:1][C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)=[N:20][C:19]2[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=2)[N:13]=1

Participants

4

Reactant 3

HCID 166592,3-DichloroquinoxalineHCID 31236PhenoxyethanolHCID 178418922HCID 178418922, compound

Product 1

HCID 22036340HCID 22036340, compound

Procedure

The title compound was prepared according to the procedure described in Example 1, Step 1, starting from 2-phenoxyethanol (3.7 g, 26.8 mmol), 2,3-dichloroquinoxaline (1.33 g, 6.7 mmol) and KO-t-Bu (0.75 g, 6.7 mmol): yield 0.74 g (37%); mp 99.5-101.5° C., HRMS m/z calcd for C16H13CIN2O2(M)+300.0666, found 300.0672. Anal. (C16H13CIN2O2) C, H, N.

Sources & evidence

ORD record
ord-3bd268dde30845da893f02ab3b29a6d4
Source dataset
uspto-grants-2006_07
Patent number
US07071180B2

Reaction notes

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