1-Ethylpiperazine → HCID 22036344, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 4, Step 2, starting from 2-chloro-3-(2,3-dihydro-1,4-benzodioxin-2-ylmethoxy)pyrazine* (150 mg, 0.54 mmol) and N-ethylpiperazine (219 mg, 1.92 mmol) with the exception that a final extraction step between EtOAc and 5% aqueous NaOH was carried out. This gave 128 mg (66%) of the title product. HRMS m/z calcd for C19H24N4O3(M)+356.1848, found 356.1848. Anal. (C19H24N4O3) C, H, N.

Provenance & Evidence