Piperazine → HCID 22036547, compound

HRID 1789749Notes

Reaction equation

HRID 1789749 reaction equation
Cl[C:2]1[C:7]([Cl:8])=[N:6][C:5]([CH3:9])=[C:4]([CH3:10])[N:3]=1.[NH:11]1[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]1>>[Cl:8][C:7]1[C:2]([N:11]2[CH2:16][CH2:15][NH:14][CH2:13][CH2:12]2)=[N:3][C:4]([CH3:10])=[C:5]([CH3:9])[N:6]=1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 128278002,3-Dichloro-5,6-dimethylpyrazine

Product 1

HCID 22036547HCID 22036547, compound

Procedure

The title compound was prepared according, to the procedure described in Example 90. Step 1, starting from 2,3-dichloro-5,6-dimethylpyrazine*(0.60 g, 3.39 mmol) and piperazine (0.88 g, 10.2 mmol). Yield 0.51 g (66%). MS m/z 226 (M)+.

Sources & evidence

ORD record
ord-ea7442f0cb4e480d9edccf434b38b7b6
Source dataset
uspto-grants-2006_07
Patent number
US07071180B2

Reaction notes

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