4-Methoxybenzyl alcohol → HCID 22036280, compound

HRID 1789771Notes

Reaction equation

HRID 1789771 reaction equation
Cl[C:2]1[C:7]([N:8]2[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]2)=[N:6][CH:5]=[CH:4][N:3]=1.[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][OH:21])=[CH:18][CH:17]=1>>[CH3:14][O:15][C:16]1[CH:23]=[CH:22][C:19]([CH2:20][O:21][C:2]2[C:7]([N:8]3[CH2:13][CH2:12][NH:11][CH2:10][CH2:9]3)=[N:6][CH:5]=[CH:4][N:3]=2)=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 77384-Methoxybenzyl alcoholHCID 140864382-Chloro-3-(piperazin-1-yl)pyrazine

Product 1

HCID 22036280HCID 22036280, compoundYield 72%

Procedure

The title compound was prepared according to the procedure of Example 90, Step 2, starting from 2-chloro-3-(1-piperazinyl)pyrazine (0.80 g, 4.0 mmol; from Example 90, Step 1) and 4-methoxybenzyl alcohol (0.88 g, 6.4 mmol). Oil; yield 72%. MS m/z 301 (M+H)+.

Sources & evidence

ORD record
ord-0459f422d40948fabce3b5626e5172db
Source dataset
uspto-grants-2006_07
Patent number
US07071180B2

Reaction notes

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