HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetylsulfanylmethyl-3-(2-amino-pyridin-4-yl)-propionic acid ethyl ester → 2-(2-Amino-pyridin4-ylmethyl)-3-mercapto-propionic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetylsulfanylmethyl-3-(2-amino-pyridin-4-yl)-propionic acid ethyl ester | HCID 54149928 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 2-(2-Amino-pyridin4-ylmethyl)-3-mercapto-propionic acid | HCID 10176712 | — |
Reaction Steps
2-Acetylsulfanylmethyl-3-(2-amino-pyridin4-yl)-propionic acid ethyl ester (52 mg, 0.13 mmol) was dissolved in conc. HCl (2 mL) under argon. The solution was heated to reflux for 1 h. Concentration under reduced pressure gave the title compound as the hydrochloride salt (32 mg, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071175B1 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-4bf3e9ebafb04352b1ad44652b3c3909 |
| Source note | uspto-grants-2006_07 |