HCID 54201262, compound → HCID 22036122, compound

HRID 1789878Notes

Reaction equation

HRID 1789878 reaction equation
C([O:3][C:4](=[O:28])[CH:5]([CH2:13][C:14]1[CH:15]=[N:16][C:17]([NH:20]C(OC(C)(C)C)=O)=[CH:18][CH:19]=1)[CH:6]([S:9]C(=O)C)[CH2:7][CH3:8])C>Cl>[NH2:20][C:17]1[N:16]=[CH:15][C:14]([CH2:13][CH:5]([CH:6]([SH:9])[CH2:7][CH3:8])[C:4]([OH:28])=[O:3])=[CH:19][CH:18]=1

Participants

3

Reactant 1

HCID 54201262HCID 54201262, compound

Product 1

HCID 22036122HCID 22036122, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

A solution of 3-acetylsulfanyl-2-(6-tert-butoxycarbonylamino-pyridin-3-ylmethyl)-pentanoic acid ethyl ester/C (4.3 mg; 0.01 mmol) in concentrated HCl (2 mL) was refluxed under argon for 1.5 hours. The reaction mixture was allowed to cool to room temperature and concentrated under reduced pressure to afford 2.9 mg of the title compound as the hydrochloride salt.

Workup

  1. concentrationconcentrated under reduced pressure

Sources & evidence

ORD record
ord-f4253a0b4cec48dc8dd43cf5d0ced6ec
Source dataset
uspto-grants-2006_07
Patent number
US07071175B1

Reaction notes

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