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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1789919Generated: October 30, 2026

HCID 53756755, compound → HCID 22036108, compound

https://huagongshe.com/reaction/1789919

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 53756755HCID 53756755—
SolventHydrochloric AcidHCID 313—
ProductHCID 22036108HCID 22036108—

Reaction Steps

2-Acetylsulfanylmethyl-3-(6-tert-butoxycarbonylamino-pyridin-3-yl)4-phenyl-butyric acid ethyl ester (0.14 g, 0.3 mmol) was dissolved in conc. HCl (5.0 mL). The solution was heated to reflux for 4.5 h under argon. Concentration under reduced pressure gave the title compound as the hydrochloride salt (100 mg, 98%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071175B1
Source datasetuspto-grants-2006_07
ORD IDord-1cfb6a7fe4ee45cf909ed85a4f33fcad
Source noteuspto-grants-2006_07