Chloroform → HCID 22036129, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of N-[5-(1-hydroxy-butyl)-pyridin-2-yl]-2,2-dimethyl-propionamide (1.025 g, 4.09 mmol) in trichloromethane (12 mL), thionylchloride (6 mL) was added and the mixture was heated to 55° C. for 1 h. Then the solution was concentrated under reduced pressure to leave crude N-[5-(1-chloro-butyl)-pyridin-2-yl]-2,2-dimethyl-propionamide hydrochloride as a colourless solid.

Provenance & Evidence