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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790433Generated: November 2, 2026

1-(2-Bromoethyl)-4-methoxybenzene → 1-[1-(4-Methoxyphenethyl)piperidin-4-yl]-6-acetamidomethylindoline

https://huagongshe.com/reaction/1790433

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Bromoethyl)-4-methoxybenzeneHCID 84427—
Reactant1-(Piperidin-4-yl)-6-acetamidomethylindolineHCID 22038275—
Product1-[1-(4-Methoxyphenethyl)piperidin-4-yl]-6-acetamidomethylindolineHCID 2203816053.7%

Reaction Steps

1-(Piperidin-4-yl)-6-acetamidomethylindoline (250 mg) and 4-methoxyphenethyl bromide (240 mg) were treated as in Example 2 to give the title compound (200 mg) as a white powder (yield: 53%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071201B2
Source datasetuspto-grants-2006_07
ORD IDord-cfd9ed927294493280549e069f5a78b4
Source noteuspto-grants-2006_07