HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Bromoethyl)-4-chlorobenzene → 1-[1-(4-Chlorophenethyl)piperidin-4-yl]-6-acetamidomethylindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Bromoethyl)-4-chlorobenzene | HCID 23029 | — |
| Reactant | 1-(Piperidin-4-yl)-6-acetamidomethylindoline | HCID 22038275 | — |
| Product | 1-[1-(4-Chlorophenethyl)piperidin-4-yl]-6-acetamidomethylindoline | HCID 22037914 | 63.7% |
Reaction Steps
1-(Piperidin-4-yl)-6-acetamidomethylindoline (250 mg) and 4-chlorophenethyl bromide (240 mg) were treated as in Example 2 to give the title compound (240 mg) as white scaly crystals (yield: 63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-2572e495efd94b7a846d1b4132a3a55c |
| Source note | uspto-grants-2006_07 |