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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790477Generated: October 30, 2026

4-(2-Bromoethyl)benzenesulfonamide → 1-[1-(4-Sulfamoylphenethyl)-piperdin-4-yl]-6-methoxyindoline

https://huagongshe.com/reaction/1790477

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Bromoethyl)benzenesulfonamideHCID 14485091—
Reactant1-(Piperidin-4-yl)-6-methoxyindolineHCID 22038180—
Product1-[1-(4-Sulfamoylphenethyl)-piperdin-4-yl]-6-methoxyindolineHCID 2203821513.1%

Reaction Steps

1-(Piperidin-4-yl)-6-methoxyindoline (350 mg) and 4-sulfamoylphenethyl bromide (340 mg) were treated as in Example 2 to give the title compound (70 mg) as a brown powder (yield: 13%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071201B2
Source datasetuspto-grants-2006_07
ORD IDord-13a1790e7fce45129ffc70eafaf88007
Source noteuspto-grants-2006_07