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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790479Generated: November 1, 2026

1-(Piperidin-4-yl)-6-methoxyindoline → 1-{1-[2-(6-Benzothiazolyl)ethyl]-piperdin-4-yl}-6-methoxyindoline

https://huagongshe.com/reaction/1790479

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Piperidin-4-yl)-6-methoxyindolineHCID 22038180—
Reactant6-(2-Bromoethyl)benzothiazoleHCID 22038205—
Product1-{1-[2-(6-Benzothiazolyl)ethyl]-piperdin-4-yl}-6-methoxyindolineHCID 2203821282.6%

Reaction Steps

6-(2-Bromoethyl)benzothiazole (0.108 g) and 1-(piperidin-4-yl)-6-methoxyindoline (0.105 g) were treated as in Example 2 to give the title compound (0.145 g) as a yellow oil (yield: 81.9%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071201B2
Source datasetuspto-grants-2006_07
ORD IDord-0d67a982b1734e37aa2e5417fc75c48c
Source noteuspto-grants-2006_07