HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-cyanoindoline → 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-cyanoindole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-cyanoindoline | HCID 11078603 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Product | 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-cyanoindole | HCID 22038064 | 84.5% |
Reaction Steps
1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-cyanoindoline (0.50 g) obtained in Example 124 and active manganese dioxide (1.00 g) were treated as in Example 288 to give the title compound (0.42 g) as a white powder (yield: 83.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-6ced43dfa1b9493f945103a2c061ea56 |
| Source note | uspto-grants-2006_07 |