Hydrochloric Acid → HCID 178488270, compound

HRID 1790665Notes

Reaction equation

HRID 1790665 reaction equation
[NH2:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[OH:10].C(O[C:14](S)=[S:15])C.[K].Cl>N1C=CC=CC=1>[CH3:9][O:8][C:6]1[CH:5]=[CH:4][C:3]2[O:10][C:14]([SH:15])=[N:1][C:2]=2[CH:7]=1

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 8823Ethyl xanthateHCID 14191082-Amino-4-methoxyphenolHCID 5462222Potassium

Product 1

HCID 178488270HCID 178488270, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

The mixture containing 2-amino-4-methoxyphenol(1 eq) and O-ethylxanthic acid, potassium salt (1.1 eq) in pyridine was refluxed for two hours. The resultant mixture was poured in to ice/water containing hydrochloric acid to yield a 5-methoxybenzoxazole-2-thiol as a tan solid. MS: MH+=182

Workup

  1. temperaturewas refluxed for two hours

Sources & evidence

ORD record
ord-5bb9ac08edac4f298e8c88f6c4bce75c
Source dataset
uspto-grants-2006_07
Patent number
US07071216B2

Reaction notes

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