HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790720Generated: October 29, 2026
4-Bromobenzaldehyde → HCID 21037207, compound
https://huagongshe.com/reaction/1790720
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Bromobenzaldehyde | HCID 70741 | — |
| Reactant | {4-[2-Methoxy-4-(methylamino)-5-nitrophenoxy] (2-pyridyl)}-n-methylcarboxamide | HCID 131725843 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21037207 | HCID 21037207 | — |
Reaction Steps
A mixture of diamine 1 (137 mg, 0.36 mmol) and 4-bromobenzaldehyde (66 mg, 0.50 mmol) in dry dioxane (2 mL) was heated to 100° C. for 16 h. The reaction mixture was allowed to cool to rt and was then concentrated. The resulting residue was purified by reverse phase HPLC to finish 2 as the TFA salt: LCMS m/z 437.1, tR=2.16 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07071216B2 |
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| Source dataset | uspto-grants-2006_07 |
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| ORD ID | ord-578aafd6133147929ebb566b7654c689 |
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| Source note | uspto-grants-2006_07 |
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