1,2-Ethanediamine, N1,N2-bis(phenylmethyl)-, acetate (1:2) → Benzathine

Participants

Reaction Steps

A solution of 15.14 g of benzathine diacetate in 160 ml demineralised water was added over 15 minutes to the decolorized solution at 150 to 20° C. The mixture was agitated for 30 minutes at 15° to 20° C., cooled to 0° to +5° C. and agitated for 1 hour. The mixture was filtered and washed 3 times with 50 ml of water. It was thoroughly squeezed under a nitrogen flow to obtain 28.52 g of the benzathine salt of the condensation product of 7-ACT with COMBA. A sample was dried for analysis.

Provenance & Evidence