HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-N'-hydroxybenzene-1-carboximidamide → 2,5-bis(4-cyanophenyl)furan
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-N'-hydroxybenzene-1-carboximidamide | HCID 2756838 | — |
| Reactant | 4-(2-furyl)benzonitrile | HCID 3419540 | — |
| Solvent | Benzonitrile | HCID 7505 | — |
| Product | 2,5-bis(4-cyanophenyl)furan | HCID 622985 | — |
Reaction Steps
in good yield. In contrast, under N-coupling conditions the benzamidoxime was converted to benzonitrile (Anbazhagan et al., (2002) Tetrahedron Lett. 43: 4221) and attempted Heck coupling of 4-bromobenzamidoxime with 2(4-cyanophenyl)furan yielded 2,5-bis(4-cyanophenyl)furan.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071338B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-23c53c47db3d41769913a28db1a35118 |
| Source note | uspto-grants-2006_07 |