Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790948Generated: November 2, 2026

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)amide → 2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-amide

https://huagongshe.com/reaction/1790948

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chlorophenyl)amideHCID 9055843—
Reactant5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042092—
Product2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-amideHCID 86585106—

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-amide was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071332B2
Source datasetuspto-grants-2006_07
ORD IDord-f1249bb3463e43fc971683f1618fa3f1
Source noteuspto-grants-2006_07