HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitro-4-(3-trifluoromethylpyridin-2-YL)benzoic acid → 2-Amino-4-[3-(trifluoromethyl)-2-pyridinyl]benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitro-4-(3-trifluoromethylpyridin-2-YL)benzoic acid | HCID 22030167 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Amino-4-[3-(trifluoromethyl)-2-pyridinyl]benzoic acid | HCID 22030253 | — |
Reaction Steps
Hydrogenate the solution of 2-nitro-4-(3-trifluoromethyl-pyridin-2-yl)-benzoic acid (3.84 mmol) in 95% EtOH (100 mL) with 10% Pd-C (150 mg) for over night. Filter through a celite pad and concentrate the filtrate to give 2-amino-4(3-trifluoromethyl-pyridin-2-yl)-benzoic acid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074799B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-5526c94546d94210aab6ec50f967604d |
| Source note | uspto-grants-2006_07 |