HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 178436303, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Benzonitrile, 3-ethyl- | HCID 96692 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178436303 | HCID 178436303 | 46% |
Reaction Steps
3-Ethyl-benzonitrile (400 mg, 3.05 mmol) with 5 M hydroxylamine hydrochloride (0.61 mL) and 1 M sodium hydroxide (3.05 mL) in ethanol (3 mL) were stirred at room temperature for 60 h. Work up as in example 4 afforded 230 mg (46%) of 3-ethyl-N-hydroxy-benzamidine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074809B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-08c518ddca984a52aaff357143fecc4d |
| Source note | uspto-grants-2006_07 |