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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1792021Generated: October 31, 2026

Trifluoroacetic acid → HCID 69542360, compound

https://huagongshe.com/reaction/1792021

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactant4-[7-(2-Methoxyphenyl)-1-(ethoxycarbonylmethyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl esterHCID 23536963—
ProductHCID 69542360HCID 69542360—

Reaction Steps

4-[7-(2-Methoxyphenyl)-1-(ethoxycarbonylmethyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester (10 mg) was dissolved in trifluoroacetic acid (0.5 ml), and the reaction mixture was stirred at room temperature for 30 minutes. After the solvent was removed, the residue was purified by reversed phase high performance liquid chromatography to give 4.92 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07074798B2
Source datasetuspto-grants-2006_07
ORD IDord-518e1b1ab51c4b65998c1f7a79d814ce
Source noteuspto-grants-2006_07