Methanol → N-(4'-chlorobiphenyl-4-yl)-3-[4-(4-methylpiperidin-1-ylmethyl)phenyl]propionamide

HRID 179208Notes

Reaction equation

HRID 179208 reaction equation
[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[CH3:39][OH:40].[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([NH:14][C:15]([CH:16]=[CH:17][c:18]3[cH:19][cH:20][c:21]([CH2:24][N:25]4[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]4)[cH:22][cH:23]3)=[O:32])[cH:12][cH:13]2)[cH:6][cH:7]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[cH:9][cH:10][c:11]([NH:14][C:15]([CH2:16][CH2:17][c:18]3[cH:19][cH:20][c:21]([CH2:24][N:25]4[CH2:26][CH2:27][CH:28]([CH3:31])[CH2:29][CH2:30]4)[cH:22][cH:23]3)=[O:32])[cH:12][cH:13]2)[cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 8857Ethyl AcetateHCID 68816314N-[4-(4-chlorophenyl)phenyl]-3-[4-[(4-methylpiperidin-1-yl)methyl]phenyl]prop-2-enamide

Product 1

HCID 57845688N-(4'-chlorobiphenyl-4-yl)-3-[4-(4-methylpiperidin-1-ylmethyl)phenyl]propionamide

Sources & evidence

ORD record
ord-c0a155776855433cb2f940e3ae20cebb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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