HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Bromo-4-chloroquinoline → 6-Bromo-4-[4-(2-pyridyloxy)piperidino]quinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Bromo-4-chloroquinoline | HCID 5139537 | — |
| Reactant | 2-(Piperidin-4-yloxy)pyridine dihydrochloride | HCID 14674154 | — |
| Product | 6-Bromo-4-[4-(2-pyridyloxy)piperidino]quinoline | HCID 22032069 | 79.4% |
Reaction Steps
500 mg 6-bromo-4-chloroquinoline and 540 mg 2-(4-piperidyloxy) pyridine dihydrochloride were reacted by the same method as in Production Example 82, to give 629 mg of the title compound as an orange oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074801B1 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-2b980d3bc2484497869d7efaf50a8779 |
| Source note | uspto-grants-2006_07 |