Ethyl 4-piperidinecarboxylate → HCID 22031326, compound

HRID 1792441Notes

Reaction equation

HRID 1792441 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2Cl.[NH:13]1[CH2:18][CH2:17][CH:16]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[N:13]1[CH2:18][CH2:17][CH:16]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 70770Ethyl 4-piperidinecarboxylateHCID 51395376-Bromo-4-chloroquinoline

Product 1

HCID 22031326HCID 22031326, compoundYield 64.1%

Procedure

500 mg 6-bromo-4-chloroquinoline and 340 mg ethyl 4-piperidine carboxylate were reacted by the same method as in Production Example 74, to give 480 mg of the title compound as a yellow oil.

Sources & evidence

ORD record
ord-f7a48dd0422e4d15afe9cbf385fb152a
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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