Hydrazine hydrate (1:1) → HCID 23537414, compound

HRID 1792463Notes

Reaction equation

HRID 1792463 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:11]([O:13]CC)=O)=[CH:9][N:10]=2)[CH:7]=1.O.[NH2:17][NH2:18]>C(O)C>[Br:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([C:11]([NH:17][NH2:18])=[O:13])=[CH:9][N:10]=2)[CH:7]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 22031055Ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate

Product 1

HCID 23537414HCID 23537414, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 1.94 g ethyl 6-bromoimidazo[1,2-a]pyridine-3-carboxylate, 6 mL hydrazine monohydrate and 20 mL ethanol was heated for 1 hour under reflux. The precipitated crystals were collected by filtration, washed with ethanol and dried under reduced pressure by a vacuum pump to give 1.71 g of the title compound as pale yellow crystals.

Workup

  1. temperaturewas heated for 1 hour
  2. temperatureunder reflux
  3. filtrationThe precipitated crystals were collected by filtration
  4. washwashed with ethanol
  5. customdried under reduced pressure by a vacuum pump

Sources & evidence

ORD record
ord-c14ea3baa17245c0a6469ad64bce125d
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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