Hydrochloric Acid → HCID 178434501, compound

HRID 1792556Notes

Reaction equation

HRID 1792556 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]4[C:19]([CH3:42])=[N:20][N:21](C(C5C=CC=CC=5)(C5C=CC=CC=5)C5C=CC=CC=5)[CH:22]=4)[CH:16]=3)[N:11]=[CH:10][CH:9]=2)[CH2:4][CH2:3]1.[ClH:43]>>[ClH:43].[ClH:43].[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]4[C:19]([CH3:42])=[N:20][NH:21][CH:22]=4)[CH:16]=3)[N:11]=[CH:10][CH:9]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22031710HCID 22031710, compound

Product 1

HCID 178434501HCID 178434501, compound

Procedure

247 mg 4-(4-methylpiperazin-1-yl)-6-(3-methyl-1-trityl-1H-4-pyrazolyl)quinoline obtained in Example 168 and 3.4 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 163, to give 147 mg of the title compound as yellow crystals.

Sources & evidence

ORD record
ord-86b144d1260a4ebc92968a75d0aa8754
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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