Hydrochloric Acid → HCID 22032345, compound

HRID 1792557Notes

Reaction equation

HRID 1792557 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][N:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]4[CH:19]=[N:20][N:21](C(C5C=CC=CC=5)(C5C=CC=CC=5)C5C=CC=CC=5)[CH:22]=4)[CH:16]=3)[N:11]=[CH:10][CH:9]=2)[CH2:4][CH2:3]1.[ClH:42]>>[ClH:42].[ClH:42].[CH3:1][N:2]1[CH2:3][CH2:4][N:5]([C:8]2[C:17]3[C:12](=[CH:13][CH:14]=[C:15]([C:18]4[CH:22]=[N:21][NH:20][CH:19]=4)[CH:16]=3)[N:11]=[CH:10][CH:9]=2)[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22031384HCID 22031384, compound

Product 1

HCID 22032345HCID 22032345, compound

Procedure

186 mg 4-(4-methylpiperazin-1-yl)-6-(1-trityl-1H-4-pyrazolyl)quinoline obtained in Example 169 and 2.6 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 163, to give 127 mg of the title compound as yellow crystals.

Sources & evidence

ORD record
ord-c4378fe124074f00830690e19d019395
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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