Hydrochloric Acid → HCID 22032490, compound

HRID 1792559Notes

Reaction equation

HRID 1792559 reaction equation
[CH3:1][C:2]1[C:6]([C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[N:17]2[CH2:22][CH2:21][N:20]([CH3:23])[CH2:19][CH2:18]2)=[C:5]([CH3:24])[N:4](C(C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[N:3]=1.[ClH:44]>>[ClH:44].[ClH:44].[CH3:24][C:5]1[C:6]([C:7]2[CH:8]=[C:9]3[C:14](=[CH:15][CH:16]=2)[N:13]=[CH:12][CH:11]=[C:10]3[N:17]2[CH2:18][CH2:19][N:20]([CH3:23])[CH2:21][CH2:22]2)=[C:2]([CH3:1])[NH:3][N:4]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23537629HCID 23537629, compound

Product 1

HCID 22032490HCID 22032490, compound

Procedure

75 mg 6-(3,5-dimethyl-1-trityl-1H-pyrazolyl)-4-(4-methylpiperazin-1-yl)quinoline obtained in Example 171 and 1 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 163, to give 147 mg of the title compound as pale yellow crystals.

Sources & evidence

ORD record
ord-d2be783263524ecc8467214297962b5e
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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