Hydrochloric Acid → HCID 178480768, compound

HRID 1792560Notes

Reaction equation

HRID 1792560 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[N:19]=[CH:18][CH:17]=[C:16]4[N:23]3[CH2:28][CH2:27][N:26]([CH3:29])[CH2:25][CH2:24]3)=[CH:11][N:10](C(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)[N:9]=2)=[CH:4][CH:3]=1.[ClH:49]>>[ClH:49].[ClH:49].[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:12]([C:13]3[CH:14]=[C:15]4[C:20](=[CH:21][CH:22]=3)[N:19]=[CH:18][CH:17]=[C:16]4[N:23]3[CH2:24][CH2:25][N:26]([CH3:29])[CH2:27][CH2:28]3)=[CH:11][NH:10][N:9]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 23537619HCID 23537619, compound

Product 1

HCID 178480768HCID 178480768, compound

Procedure

371 mg 6-[3-(4-fluorophenyl)-1-trityl-1H-pyrazolyl]-4-(4-methylpiperazin-1-yl)quinoline obtained in Example 172 and 4.5 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 163, to give 201 mg of the title compound as pale yellow crystals.

Sources & evidence

ORD record
ord-06da356feb9d45e7b65ac008980ac74b
Source dataset
uspto-grants-2006_07
Patent number
US07074801B1

Reaction notes

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