Hydrochloric Acid → HCID 178434507, compound

HRID 1792567Notes

Reaction equation

[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][N:13]([C:16]3[C:25]4[C:20](=[CH:21][CH:22]=[C:23]([C:26]5[C:27]([CH3:50])=[N:28][N:29](C(C6C=CC=CC=6)(C6C=CC=CC=6)C6C=CC=CC=6)[CH:30]=5)[CH:24]=4)[N:19]=[CH:18][CH:17]=3)[CH2:12][CH2:11]2)=[O:9])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[ClH:51]>>[ClH:51].[ClH:51].[C:1]1([NH:7][C:8]([N:10]2[CH2:15][CH2:14][N:13]([C:16]3[C:25]4[C:20](=[CH:21][CH:22]=[C:23]([C:26]5[C:27]([CH3:50])=[N:28][NH:29][CH:30]=5)[CH:24]=4)[N:19]=[CH:18][CH:17]=3)[CH2:12][CH2:11]2)=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 23537497HCID 23537497, compound

Product 1

HCID 178434507HCID 178434507, compound

Procedure

63 mg N1-phenyl-4-[6-(3-methyl-1-trityl-1H-pyrazolyl)-4-quinolyl]-1-piperazine carboxamide obtained in Example 181 and 0.7 mL of 5 N hydrochloric acid were reacted in the same manner as in Example 163, to give 30 mg of the title compound as pale yellow crystals.

Sources & evidence

ORD record: ord-e8583160cece4bc5b5113fa62fcc4dba
Source dataset: uspto-grants-2006_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07074801B1

Reaction notes

Loading…